Graduate School of Agricultural and Life Sciences, The University of Tokyo

Main articles published in academic journals

[ BSE, prion ]

Papers written in English

• Onodera T and Sakudo A. Prions. Chapter 12, Foodborne Viral Pathogens pp 237-256, Edited by Grant S. Hansman and Peter A. White, CRC Press, 2017.
• Onodera T and Sakudo A. Prion, Laboratory models for foodborne infections. Chapter 6, Taylor and Francis CRC Press, 2017.
• Onodera T. Dual role of cellular prion protein in normal host and Alzheimer’s diseases. Proc. Jpn. Acad. Ser. B 93:155-173, 2017.
• Sato D, Haritani M, Onishi R, Furusaki K, Yokoyama T,Onodera T and Yukawa M. Evaluations of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for prions. Prion 11:s47, 2017.
• Nakashima R, Kawamoto M, Miyazaki S, Onishi R, Furusaki K, Sakudo A and Onodera T. Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses. J. Vet. Med. Sci. 79:939-942, 2017.
• Onodera T and Sakudo A. Prions. Chapter 10, Molecular Biology of Foodborne Viral Pathogens, Edited by Don Liu, CRC Press, 2016.
• Yokoyama T, Sohn H.J and Onodera T. Animal prion disease workshop:pdated diagnosis and epidemiology of animal prion diseases for food safety and security. Food Safety (Japanese Food Safety Commission) pp.103-104, 2016. https://www.jstage.jst.go.jp/article/foodsafetyfscj/4/4/4_2016024/_article.
• Onodera T and Sakudo A. Bovine spongiform encephalopathy. Molecular detection of animal viral pathogens. Chapter 99, 877-888, Edited by Dongyou Liu, CRC Press, 2016.
• Sakudo A and Onodera T. Chronic Wasting Disease. Molecular detection of animal viral pathogens. Chapter 100, 889-897, Edited by Dongyou Liu, CRC Press, 2016.
• Onodera T, Sakudo A, Tsubone H and Itohara S. Review of studies that have used knockout mice to assess normal function of prion protein under immunological or pathophysiological stress. Microbiol. Immunol. 58: 361-374, 2014.
• Hosoi, Y., Asai, T., Koike, R., Tsuyuki, M. and Sugiura, K. Use of veterinary antimicrobial agents from 2005 to 2010 in Japan. International Journal of Antimicrobial Agents 41(5):489-90,2013.　appendix table(PDF)
• Onodera, T. and Sugiura, K. History of Japanese BSE. Bull. Soc Franco-Japonais Sci Vet, in press.
• Onodera, T., Sugiura, K. BSE situation in East Asia. Bull. Soc Franco-Japonais Sci Vet, in press.
• Shinoda N, Takagi M, Hayakawa T, Onodera T, and Sugiura K. Development of primers for detection of multiple cervid species in animal feed. J. Food Safety. 30:916-923, 2010.
• Sakudo, A., Xue, G., Kawashita, N., Ano, Y., Takagi, T., Shintani, H., Tanaka, Y., Onodera, T., Ikuta, K. Structure of the prion protein and gene: an analysis using bioinformatics and computer simulation. Cur Protein Pept Sci 11(2):166-179, 2010.
• Ano Y, Nakayama H, Sakudo A, Sawano Y, Tanokura M, Itohara S, Onodera T. Intestinal uptake of amyloid beta protein through columnar epithelial cells in suckling mice. Histol Histopathol 24(3):283-292, 2009.
• Sugiura K, Kusama T, Yoshida T, Shinoda N, Onodera T. Risk of introduction of BSE into Japan by the historical importation of live cattle from the United Kingdom. J Vet Med Sci 71(2):133-138, 2009.
• Nitta K, Sakudo A, Masuyama J, Xue G, Sugiura K, Onodera T. Role of cellular prion proteins in the function of macrophages and dendritic cells. Protein Pept Lett 16(3):239-246, 2009.
• Ano Y, Sakudo A, Nakayama H, Onodera T. Uptake and dynamics of infectious prion protein in the intestine. Protein Pept Lett 16(3):247-255, 2009.
• Sugiura K, Kikuchi E, Onodera T. Updated prediction for the BSE epidemic in dairy cattle in Japan. Prevent Vet Med 89:272-276, 2009.
• Shinoda, N., Yoshida, T., Kusama, T., Takagi, M., Onodera, T., and Sugiura, K. Development of primers for the detection of heat-inactivated cetacean materials in porcine meat and bone meal. J. Food Protect 72(7):1496-1499, 2009.
• Kobayashi, S., Ano, Y., Sakudo, A., Yukawa, M., Sugiura, K., Manabe, N., Nakayama, H., and Onodera, T. Quantification of PrPc in bovine peripheral tissues: analysis in wild-type and PrPc-deficient cattle. Mol Med Report 2:561-566, 2009.
• Sugiura, K., Fujii, T., and Onodera, T. Introduction of a pet food safety law in Japan. Vet Ital 45:297-303, 2009.
• Sugiura, K., Murray, N., Shinoda, N., and Onodera, T. Impact of potential changes to the current BSE surveillance programs for slaughter cattle and fallen-stock in Japan. J Food Protect 72(7):1463-1467, 2009.
• Onodera, T., Xue, G., Tsuchiya, K., Hosokawa, T., Ueda, S., Sugiura, K. Creation de la Commission Japonaise de la Securite Sanitaire des Aliments (CSSA) et son role par rapport a l’Encephalopathie Spongiforme Bovine (ESB). Bull l’Acad Vet France Tome 162(2):181-186, 2009.
• Kusama, T., Onodera, T., Sugiura, K. Feed controls implemented in Japan for eradication of BSE. Vet Ital 45:287-295, 2009.
• Onodera, T., Sakudo, A., Xue, G., Zanusso, G., Sugiura, K. Slow viruses. In Molecular Detection of Foodborn Pathogen, Chapter 9, pp. 111-123, 2009.
• Sugiura, K., Yamatani, S., Watahara, M., and Onodera, T. ECOFEED, animal feed from recycled food waste. Vet Ital 45:397-404, 2009.
• Yoshida, T., Shinoda, N., Kusama, T., Kadowaki, K., Sugiura, K. Developing a PCR primer for detection of DNA of porcine-origin using mtATP6 as target sequence. J Food Hyg Soc Jpn 50:89-92, 2009.
• Noboru Manabe, Jun-You Li, Ichiro Onoyama, Yutaka Sendai, Yoshito Aoyagi, Takashi Onodera, Yasuhiro Yoshikawa. Role of prion homo-knockout cattle on prevention of spontaneous bovine spongiform encephalopathy. Proc Korea Fed Sci Tech Soc 5:52-58, 2009.
• Sugiura, K. and Onodera, T. 2008. Cattle traceability sysytem in Japan for bovine spongiform encephalopathy. Vet Ital 44: 519-526, 2008
• Nishimura, T., Sakudo, A., Xue, G., Ikuta, K., Yukawa, M., Sugiura, K., Onodera, T. Establishment of a new glial cell line from hippocampus of prion protein gene-deficient mice. Biochem Biophys Res Commun 377:1047-1050, 2008.
• Zhu X, Matoba S, Hara K, Ano Y, Kobayashi S, Tsunekawa N, Kanai Y, Manabe N, Onodera T, Kurohmaru M.: Ratio of peripheral nervous tissues in tongues, skeletal muscles and intestines in cows. Okajimas Folia Anat Jpn 85(2):73-77, 2008.
• Ano Y, Nakayama H, Sakai Y, Sakudo A, Endo M, Ebisu S, Li J, Uetsuka K, Manabe N, Onodera T. Incorporation of beta-amyloid protein through the bovine ileal epithelium before and after weaning: model for orally transmitted amyloidoses. Microbiol Immunol 52(8):429-434, 2008.
• Sinoda, N., Kusama, T., Yoshida, T., Kadowaki, K., Onodera, T., Sugiura, K. : Developing PCR primers using a new computer program for detection of multiple animal derived materials in feed. J Food Protect 71:2257-2262, 2008
• Sugiura, K., Onodera, T. Cattle traceability system in Japan for bovine spongiform encephalopathy. Vet Ital 44:519-526, 2008.
• Sakudo, A., Wu, G.Y., Onodera, T., and Ikuta, K. Transient production of abnormal prion protein requires the octapeptide repeat region of prion protein (PrP) in PrP-deficient neuronal cell line. Biochem Biophys Res Commun 365:164-169, 2008.
• Nasu-Nishimura, Y., Taniuchi, Y., Nishimura, T., Sakudo, A., Nakajima, K., Ano, Y., Sugiura, K., Sakaguchi, S., Itohara, S., and Onodera, T. Cellular prion protein prevents brain damage after encephalomyocarditis virus (EMCV) infection in mice. Arch Virol 153:1007-1012, 2008.
• Hosokawa, T., Ono, F., Tuchiya, K., Sato, I., Takeyama, N., Ueda, S., Zanusso, G., Takahashi, H., Sata, T., Sakudo, A., Suguira, K., Baj, A., Toniolo, A., Yoshikawa, Y., and Onodera, T. Distinct immunohistochemical localization of Kuru plaques using novel anti-PrP monoclonal antibodies. Microbiol Immunol 52:25-29, 2008.
• Sakudo, A., Taniuchi, Y., Kobayashi, T., Onodera, T., and Ikuta, K. Normal cytochrome c oxidase activity in prion protein knockout mice. Protein Pept Lett 15:250-254, 2008.
• Hosokawa, T., Tuchiya, K., Sato, I., Takeyama, N., Ueda, S., Tagawa, Y., Kimura, K.M., Nakamura, I., Wu, G., Sakudo, A., Casalone, C., Mazza, M., Caramelli, M., Takahashi, H., Sata, T., Sugiura, K., Baj, A., Toniolo, A., and Onodera, T. A monoclonal antibody (1D12) defines novel distribution pattern of prion protein (PrP) as granules in nucleus: implication for mechanisms of nuclear localization of PrP. Biochem Biophys Res Commun 366:657-663, 2008.
• Sakudo, A., Onodera, T., and Ikuta, K. No alteration of PrPres level and incubation period in a transgenic mouse model expressing Borna disease virus phosphorprotein. Neurosci Lett 431:81-85, 2008.
• Xue, G., Sakudo, A., Kim, C.K., and Onodera, T. Coordinate regulation of bovine prion protein gene promoter activity by two Sp1 binding site polymorphism. Biochem Biophys Res Commun 372:530-535, 2008.
• Wu, G.Y., Nakajima, K., Ano, Y., Takeyama, N., Yukawa, M, Taniuchi, Y., Sakudo, A., and Onodera, T. Species-specific anti-apoptotic activity of cellular prion protein in a mouse PrP-deficient neuronal cell line transfected with mouse, hamster and bovine Prnp Neurosci Lett 466:11-15, 2008.
• Sugiura, K. and Smith, G. C. A comparison of the risk of BSE infectivity in beef from cattle younger than 21 months in Japan with that in beef from the United States as assessed by the carcass maturity score. J Food Protect 71:802-806, 2008.

Papers written in Japanese

• Takeshi Onodera and Katsuaki Sugiura,
  The circumstances behind the outbreak of BSE and its countermeasures, The Japanese Society of Veterinary History Journal Vol. 47:1-20, 2010
• Takeshi Onodera and Katsuaki Sugiura,
  Bovine spongiform encephalopathy (BSE), prion disease and late-onset infection, Kanehara Shuppan, 2009
• Takeshi Onodera,
  BSE and its diagnosis, Food Safety Dictionary, Edited by Japanese Society for Food Hygiene and Safety, Asakura Publishing, pp. 428-430, 2009
• Katsuaki Sugiura,
  Current status of efforts for livestock feed safety and future challenges, Japanese Society of Animal Science Journal, Vol. 80, 419-428, 2009
• Katsuaki Sugiura,
  History, current status and future challenges to secure livestock feed safety in Japan, Japanese Society of Animal Science Journal, Vol. 79, 445-458, 2008