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Main articles published in academic journals

[ Gut immunity, food allergy, and Food functionality]

Papers written in English

  • Tang C, Kakuta S, Shimizu K, Kadoki M, Kamiya T, Shimazu T, Kubo S, Saijo S, Ishigame H, Nakae S, Iwakura Y. Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Tregcells through modification of the intestinal microbiota. Nat Immunol. in Press.
  • Desamero MJ, Kakuta S, Chambers JK, Uchida K, Hachimura S, Takamoto M, Nakayama J, Nakayama H, Kyuwa S. Orally administered brown seaweed-derived β-glucan effectively restrained development of gastric dysplasia in A4gnt KO mice that spontaneously develop gastric adenocarcinoma. Int Immunopharmacol. 60:211-220, 2018.
  • Ono-Ohmachi A, Nakajima-Adachi H, Morita Y, Kato K, Hachimura S. Milk basic protein supplementation exerts an anti-inflammatory effect in a food-allergic enteropathy model mouse. J. Dairy Sci. 101:1852-1863, 2018.
  • Hachimura S, Totsuka M, Hosono A. Immunomodulation by food: impact on gut immunity and immune cell function.Biosci Biotechnol Biochem. 82:584-599, 2018.
  • Desamero MJ, Kakuta S, Chambers JK, Uchida K, Hachimura S, Takamoto M, Nakayama J, Nakayama H, Kyuwa S. Orally administered brown seaweed-derived β-glucan effectively restrained development of gastric dysplasia in A4gnt KO mice that spontaneously develop gastric adenocarcinoma.Int Immunopharmacol. 60:211-220, 2018.
  • Arai S, Iwabuchi N, Takahashi S, Xiao JZ, Abe F, Hachimura S. Orally administered heat-killed Lactobacillus paracasei MCC1849 enhances antigen-specific IgA secretion and induces follicular helper T cells in mice. PLoS One. 13:e0199018, 2018.
  • Uemura T, Yashiro T, Oda R, Shioya N, Nakajima T, Hachisu M, Kobayashi S, Nishiyama C, Arimura G. Intestinal Anti-Inflammatory Activity of Perillaldehyde. J. Agric. Food Chem 66(13):3443–3448, 2018.
  • Ogawa M, Yamanashi Y, Takada T, Abe K, Kobayashi S. Effect of luteolin on the expression of intestinal cholesterol transporters. J Funct Foods 36:274-279, 2017.
  • Hiraide E, Morinaga M, Hidaka H, Yamada S, Takeyama J, Kitamura N, Kaminuma O, Hiroi T, Du W, Ohashi-Doi K, Nakajima-Adachi H, Hachimura S. Oral administration of ovalbumin after sensitization attenuates symptoms in a mouse model of food allergic enteropathy. Biosci Biotechnol Biochem. 81:1967-1972, 2017.
  • Shiokawa A, Kotaki R, Takano T, Nakajima-Adachi H, Hachimura S. Mesenteric lymph node CD11b-CD103+ PD-L1High dendritic cells highly induce regulatory T cells. Immunology. 152:52-64, 2017.
  • Jia H, Hanate M, Aw W, Itoh H, Saito K, Kobayashi S, Hachimura S, Fukuda S, Tomita M, Hasebe Y, Kato H. Eggshell membrane powder ameliorates intestinal inflammation by facilitating the restitution of epithelial injury and alleviating microbial dysbiosis. Sci Rep. 7:43993, 2017.
  • Nakajima-Adachi H, Shibahara K, Fujimura Y, Takeyama J, Hiraide E, Kikuchi A, Murakami H, Hosono A, Nochi T, Wakatsuki Y, Shimojo N, Kaminogawa S, Sato R, Kiyono H, Hachimura S. Critical role of intestinal interleukin-4 modulating regulatory T cells for desensitization, tolerance, and inflammation of food allergy. PLoS One. 12:e0172795, 2017.
  • Shin N, Hanaoka K, Piao W, Miyakawa T, Fujisawa T, Takeuchi S, Takahashi S, Komatsu T, Ueno T, Terai T, Tahara T, Tanokura M, Nagano T, and Urano Y. Development of an azoreductase-based reporter system with synthetic fluorogenic substrates. ACS Chem. Biol. 12(2):558–563, 2017.
  • Miyakawa T, Kumazawa A, Fuke Y, Noshita T, Miyauchi Y, Okada M and Tanokura M. Preparation of the extracellular domain of recombinant human Toll-like receptor 6. Protein J. 36(1):28-35, 2017.
  • Okai M,* Yamamura A,* Hayakawa K, Tsutsui S, Miyazono K, Lee W-C, Nagata K, Inoue Y and Tanokura M. Insight into the transition between open and closed conformations of Thermus thermophilus carboxypeptidase. Biochem. Biophys. Res. Commun. 484(4):787–793, 2017.
    *Equal contribution
  • Mizutani H, Sugawara H, Buckle A. M Sangawa T, Miyazono K, Ohtsuka J, Nagata K, Shojima T, Nosaki S, Xu Y, Wang D, Hu X, Tanokura M and Yura K. REFOLDdb: A new and sustainable gateway to experimental protocols for protein folding.BMC Struct. Biol. 17(1):4, 2017.
  • Kodani Y,* Miyakawa T,* Komatsu T and Tanokura M. NMR-based metabolomics for simultaneously evaluating multiple determinants of primary beef quality in Japanese Black cattle. Sci. Rep. 7:41598, 2017*Equal contribution
  • Okai M,* Lee W-C,* Guan L-J, Ohshiro T, Izumi Y and Tanokura M. Crystal structure of dibenzothiophene sulfone monooxygenase BdsA from Bacillus subtilis WU-S2B. Proteins 85(6):1171-1177, 2017.*Equal contribution
  • White K, Kim M-J, Ding D, Han C, Park H-J, Meneses Z, Tanokura M, Linser P, Salvi R, and Someya S. G6pd deficiency does not affect the cytosolic glutathione or thioredoxin antioxidant defense in mouse cochlea. J. Neurosci. 37(23):5770-5781, 2017.
  • Nara M, Morii H, Sakamoto A, Miyakawa T and Tanokura M. ATR-FTIR study on synthetic peptide analogues of the Ca2+-binding sites of Ca2+-binding proteins. Peptide Science 2016 113-114, 2017.
  • Miyakawa T and Tanokura M. Structural basis for the regulation of phytohormone receptors. Biosci. Biotechnol. Biochem. 81(7):1261-1273, 2017.
  • Nakamura T, Fujiwara Y, Yamada R, Fujii W, Hamabata T, Lee MY, Maeda S, Aritake K, Roers A, Sessa WC, Nakamura M, Urade Y, *Murata T. Mast cell-derived PGD2 attenuates anaphylactic reactions in mice. J Allergy Clinical Immunology 140(2):630–632, 2017.
  • Mihara T, Mikawa S, Kaji N, Endo M, Oikawa T, Jan T-R, Ozaki H, Hori M. Therapeutic action of honokiol on postoperative ileus via downregulation of iNOS gene expression. Inflammation 40(4):1331–1341, 2017.
  • Endo M, Hori M, Mihara T, Ozaki H, Oikawa T, Odaguchi H, Hanawa T. Zingiberis Siccatum Rhizoma, the active component of the Kampo formula Daikenchuto, induces anti- inflammatory actions through α7 nicotinic acetylcholine receptor activation. Neurogastroenterol. Motil. 29(12):e13139, 2017.
  • Aoki-Yoshida A, Yamada K, Hachimura S, Sashihara T, Ikegami S, Shimizu M, Totsuka M. Enhancement of Oral Tolerance Induction in DO11.10 Mice by Lactobacillus gasseri OLL2809 via Increase of Effector Regulatory T Cells. PLoS One. 11:e0158643, 2016.
  • Nakamura A, Ohtsuka J, Kashiwagi T, Numoto N, Hirota N, Ode T, Okada H, Nagata K, Kiyohara M, Suzuki E, Kita A, Wada H and Tanokura M. In-situ and real-time growth observation of high-quality protein crystals under quasi-microgravity on earth. Sci. Rep. 6:22127, 2016.
  • Inoue A, Satoh A,Morishita M, Tokunaga Y, Miyakawa T, Tanokura M. and Ojima T. Functional heterologous expression and characterization of mannuronan C5-epimerase from the brown alga Saccharina japonica. Algal Res. 16:282-291, 2016.
  • Lu Y, Hu F, Miyakawa T and Tanokura M. Complex mixture analysis of organic compounds in yogurt by NMR spectroscopy. Metabolites 6(2):E19, 2016.
  • Xu Y, Miyakawa T, Nakamura H, Nakamura A, Imamura Y, Asami T and Tanokura M. Structural basis of unique ligand specificity of KAI2-like protein from parasitic weed Striga hermonthica. Sci. Rep. 6:31386, 2016.
  • Zheng H, Miyakawa T, Sawano Y, Asano A, Okumura A, Yamagoe S and Tanokura M. Crystal structure of human leukocyte cell-derived chemotaxin 2 (LECT2) reveals a mechanistic basis of functional evolution in a mammalian protein with an M23 metalloendopeptidase fold. J. Biol. Chem. 291(33):17133-17142, 2016.
  • Wei F, Furihata K, Zhang M, Miyakawa T and Tanokura M. Use of NMR-based metabolomics to chemically characterize the roasting process of chicory root. J. Agric. Food Chem. 64(33):6459-6465, 2016.
  • Katayama Y, Suzuki T, Ebisawa T, Ohtsuka J, Wang S, Natsume R, Lo Y-H, Senda T, Nagamine T, Hull J. J, Matsumoto S, Nagasawa H, Nagata K and Tanokura M. A class-A GPCR solubilized under high hydrostatic pressure retains its ligand binding ability.
    Biochim. Biophys. Acta 1858(9):2145-2151, 2016.
  • Wang D, Miyazono K and Tanokura M. Tetrameric structure of the restriction DNA glycosylase R.PabI in complex with nonspecific double-stranded DNA. Sci. Rep. 6:35197, 2016.
  • Han C, Ding D, Lopez M. C, Manohar S, Zhang Y, Kim M-J, Park H-J, White K, Kim Y. H, Linser P, Tanokura M, Leeuwenburgh C, Baker H, Salvi R, and Someya S. Effects of long-term exercise on age-related hearing loss in mice.J. Neurosci. 36(44):11308-11319, 2016.
  • Tsutsui N, Sakamoto T, Arisaka F, Tanokura M, Nagasawa H and Nagata K. Crystal structure of a crustacean hyperglycemic hormone (CHH) precursor suggests structural variety in the C-terminal regions of CHH superfamily members.FEBS J. 283(23):4325-4339, 2016
  • Qin H-M, Miyakawa T, Inoue A, Nishiyama R, Nakamura A, Asano A, Sawano Y, Ojima T and Tanokura M. Structure and polymannuronate specificity of a eukaryotic member of the polysaccharide lyase family 14. J. Biol. Chem. 292(6):2182-2190, 2016.
  • Kataoka M, Miyakawa T, Shimizu S, and Tanokura M. Enzymes useful for chiral compound synthesis: structural biology, directed evolution, and protein engineering for industrial use. Appl. Microbiol. Biotechnol. 100(13):5747-5757, 2016.
  • Miyakawa T, Phan A. H and Tanokura M. 14. Metabolomics study of green coffee beans. Green Coffee Bean Extract in Human Health (Bagchi D, Moriyama H and Swaroop A eds.) 217-231, CRC Press, Taylor & Francis Group, Boca Raton, Florida, USA, 2016.
  • Sugi H, Chaen S, Akimoto T, Tanokura M, Miyakawa T and Minoda H. Application of liquid cell microscopy to study of muscle proteins. Chapter 18, Liquid Cell Electron Microscopy (Ross F. M, ed.), 356-370, Cambridge University Press, Cambridge, U.K., 2016.
  • Sugi H, Akimoto T, Chaen S, Miyakawa T, Tanokura M and Minoda H. Electron microscopic visualization and recording of ATP-induced myosin head power stroke producing muscle contraction using the gas environmental chamber. Chapter 1, Muscle Contraction and Cell Motility: Fundamentals and Developments (Sugi H, ed.) 3-34, Pan Stanford Publishing, Singapore, 2016.
  • Sugi, H. Chaen S, Miyakawa T, Tanokura M. and Kobayashi T. Limitations of in vitro motility assay systems in studying molecular machansim of muscle contraction as revealed by the effect of antibodies to myosin head. Chapter 4, Muscle Contraction and Cell Motility: Fundamentals and Developments (Sugi H, ed.) 117-142, Pan Stanford Publishing, Singapore, 2016.
  • Adachi T, Kakuta S, Aihara Y, Kamiya T, Watanabe Y, Osakabe N, Hazato N, Miyawaki A, Yoshikawa S, Usami T, Karasuyama H, Kimoto-Nira H, Hirayama K, Tsuji NM. Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo. Front Immunol. 7:601, 2016.
  • Kotaki R, Wajima S, Shiokawa A, Hachimura S. Toll-like receptor 2 suppresses Toll-like receptor 9 responses in Peyer’s patch dendritic cells. Immunobiology. 220:734-43, 2015.
  • Noguchi-Shinohara M, Ono K, Hamaguchi T, Iwasa K, Nagai T, Kobayashi S, Nakamura H, Yamada M. Pharmacokinetics, safety and tolerability of rosmarinic acid in healthy individuals. PLOS One 10(5): e0126422, 2015.
  • Nara M, Morii H, Sakamoto A, Miyakawa T and Tanokura M. Infrared study on 13C-labeled synthetic peptide analogues of the Ca2+-binding site III of troponin C. Peptide Science 2015:139-140, 2015.
  • Nakamura T, Maeda S, Horiguchi K, Maehara T, Aritake K, Choi B, Iwakura Y, Urade Y, *Murata T. PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia. Nature Communications 6:7514, 2015.
  • Sasaki T, Kinoshita Y, Matsui S, Kakuta S, Yokota-Hashimoto H, Kinoshita K, Iwasaki Y, Kinoshita T, Yada T, Amano N, Kitamura T. N-methyl D-aspartate receptor co-agonist D-serine suppresses intake of high-preference food. Am J Physiol Regul Integr Comp Physiol 309(5):R561-75, 2015.
  • Tang C, Kamiya T, Liu Y, Kadoki M, Kakuta S, Oshima K, Hattori M, Takeshita K, Kanai T, Saijo S, Ohno N, Iwakura Y. Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine. Cell Host Microbe 18(2):183-97, 2015.
  • Watanabe H, Toda M, Sekido H, Fujii T, Henle T, Hachimura S, Nakajima-Adachi H. Heat treatment of egg white controls allergic symptoms and induces oral tolerance to ovalbumin in a murine model of food allergy. Mol. Nutr. Food Res. 58:394-404, 2014.
  • Park J, Miyakawa T, Shiokawa A, Nakajima-Adachi H, Tanokura M, Hachimura S. Attenuation of migration properties of CD4+ T cells from aged mice correlates with decrease in chemokine receptor expression, response to retinoic acid, and RALDH expression compared to young mice. Biosci. Biotechnol. Biochem. 78:976-80, 2014.
  • Hiraide E, Nakajima-Adachi H, Hachimura S. Oral Administration of T Cell Epitope Peptide Inhibits the Systemic IL-4 Response Elicited by an Egg-White Diet in a TCR Transgenic Mouse Model. Biosci. Microbiota Food Health. 33:47-51, 2014.
  • Shibahara K, Nakajima-Adachi H, Kaminuma O, Hiroi T, Mori A, Hachimura S. Food Allergen-induced IgE Response Mouse Model Created by Injection of in vitro Differentiated Th2 Cell Culture and Oral Antigen Intake.Biosci. Microbiota Food Health. 33:41-6, 2014.
  • Park J, Miyakawa T, Shiokawa A, Nakajima-Adachi H, Tanokura M, Hachimura S. Splenic stromal cells from aged mice produce higher levels of IL-6 compared to young mice. Mediators Inflamm. 2014:826987, 2014.
  • Nakajima-Adachi H, Kikuchi A, Fujimura Y, Shibahara K, Makino T, Goseki-Sone M, Kihara-Fujioka M, Nochi T, Kurashima Y, Igarashi O, Yamamoto M, Kunisawa J, Toda M, Kaminogawa S, Sato R, Kiyono H, Hachimura S. Peyer’s patches and mesenteric lymph nodes cooperatively promote enteropathy in a mouse model of food allergy. PLoS One. 9: e107492, 2014.
  • Kikuchi Y, Kunitoh-Asari A, Hayakawa K, Imai S, Kasuya K, Abe K, Adachi Y, Fukudome S, Takahashi Y, Hachimura S. Oral administration of Lactobacillus plantarum strain AYA enhances IgA secretion and provides survival protection against influenza virus infection in mice. PLoS One. 9:e86416, 2014.
  • Iwanaga K, Nakamura T, Maeda S, Aritake K, Hori M, Urade Y, Ozaki H, *Murata T. Mast Cell-Derived Prostaglandin D2 Inhibits Colitis and Colitis-Associated Colon Cancer in Mice. Cancer Res. 74(11):3011-9, 2014.
  • Endo M, Hori M, Ozaki H, Oikawa T, Hanawa T. Daikenchuto, a traditional Japanese herbal medicine, ameliorates postoperative ileus by anti-inflammatory action through nicotinic acetylcholine receptors. J Gastroenterol 49:1026-1039, 2014.
  • Endo M, Hori M, Ozaki H, Oikawa T, Hanawa T. Rikkunshito, a Kampo Medicine, Ameliorates Post-operative Ileus by Anti-inflammatory Action.
    J Pharmacol Sci. 124:374-385, 2014.
  • Akitsu A, Kakuta S, Saijo S, Iwakura Y. Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis. Exp Anim. 63(2):235-46, 2014.
  • Hong Zhang, Ying Lu, Hideki Ushio, Kazuo Shiomi. Development of sandwich ELISA for detection and quantification of invertebrate major allergen tropomyosin by a monoclonal antibody. Food Chemistry 01/2014 150:151-157, 2014.
  • Tsubone H, Makimura Y, Hanafusa M, Yamamoto Y, Tsuru Y, Motoi M, Amano S. Agaricus brasiliensis KA21 improves circulatory functions in spontaneously hypertensive rats. J Med Food. 2014 Mar;17(3):295-301.
  • Bohnen C, Wangorsch A, Schulke S, Nakajima-Adachi H, Hachimura S, Suzer Y, Schwantes A, Sutter G, Waibler Z, Reese G, Toda M, Scheurer S, Vieths S. Vaccination with recombinant modified vaccinia virus ankara prevents theonsetof intestinal allergy of mice. Allergy. 68:1021-8, 2013.
  • Tanioka A, Tanabe K, Hosono A, Kawakami H, Kaminogawa S, Tsubaki K, Hachimura S. Enhancement of intestinal immune function in mice by β-D-glucan from Aureobasidium pullulans ADK-34. Scand. J. Immunol. 78: 61-8, 2013.
  • Yanagibashi T, Hosono A, Oyama A, Tsuda M, Suzuki A, Hachimura S, Takahashi Y, Momose Y, Itoh K. Hirayama K, Takahashi K, Kaminogawa S. IgA production in the large intestine is modulated by a different mechanism than in the small intestine: Bacteroides acidifaciens promotes IgA production in the large intestine by inducing germinal center formation and increasing the number of IgA+ B cells. Immunobiology. 218:645-51, 2013.
  • Kobayashi S, Shinohara M, Nagai T, Konishi Y. Transport mechanisms for soy isoflavones and microbial metabolites dihydrogenistein and dihydrodaidzein across monolayers and membranes. Biosci Biotechnol Biochem 77 (11):2210-2217, 2013.
  • Idota Y, Harada H, Tomono T, Morimoto K, Kobayashi S, Kakinuma C, Miyajima C, Kasahara F, Ogihara T. Alginate enhances excretion and reduces absorption of strontium and cesium in rats. Biol Pharm Bull 36(3):485-491, 2013.
  • Nakajima-Adachi H, Koike E, Totsuka M, Hiraide E, Wakatsuki Y, Kiyono H, Hachimura S. Two distinct epitopes on the ovalbumin 323-339 peptide differentiating CD4+ T cells into the Th2 or Th1 phenotype. Biosci. Biotechnol. Biochem. 76:1979-81, 2012.
  • Onodera T, Takahashi Y, Yokoi Y, Ato M, Kodama Y, Hachimura S, Kurosaki T, Kobayashi K. Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection. Proc. Natl. Acad. Sci. U S A. 109:2485-90, 2012.
  • Kawasaki H, Ohama T, Hori M, Sato K. Establishment of mouse intestinal myofibroblast cell lines. World J Gastroenterol 19:2629-2673, 2013.
  • Kobayashi S, Katsuyama S, Wagatsuma T, Okada S, Tanabe S. Identification of a new IgE-binding epitope of peanut oleosin that cross-reacts with buckwheat. Biosci Biotechnol Biochem 76:1182-1188, 2012.
  • Sakai S, Murata T, Tsubosaka Y, Ushio H, Hori M, Ozaki H. γ-Oryzanol reduces adhesion molecule expression in vascular endothelial cells via suppression of nuclear factor-κB activation. J Agric Food Chem 60:3367-3372, 2012.
  • Hashiguchi M, Hachimura S, Ametani A, Sato T, Kojima H, Kumagai Y, Habu S, Kobata T, Kaminogawa S. Naïve CD4+ T cells of Peyer’s patches produce more IL-6 than those of spleen in response to antigenic stimulation. Immunol Lett 141(1):109-115, 2011.
  • Shimizu, M. Hachimura, S. Gut as a target for functional food. Trend. Food Sci. Technol 22: 646-650, 2011.
  • Burggraf M, Nakajima-Adachi H, Hachimura S, Ilchmann A, Pemberton AD, Kiyono H, Vieths S, Toda M. Mol Nutr Food Res 55: 1475-83, 2011.
  • Hiramatsu Y, Hosono A, Konno T, Nakanishi Y, Muto M, Suyama A, Hachimura S, Sato R, Takahashi K, Kaminogawa S. Orally administered Bifidobacterium triggers immune responses following capture by CD11c+ cells in Peyer’s patches and cecal patches. Cytotechnology 63: 307-17, 2011.
  • Ohashi T, Iizuka S, Shimada Y, Eto Y, Ida H, Hachimura S, Kobayashi H. Oral administration of recombinant human acid α-glucosidase reduces specific antibody formation against enzyme in mouse. Mol Genet Metab. 103: 98-100, 2011.
  • Tsuda M, Hosono A, Yanagibashi T, Kihara-Fujioka M, Hachimura S, Itoh K, Hirayama K, Takahashi K, Kaminogawa S. Intestinal commensal bacteria promote T cell hyporesponsiveness and down-regulate the serum antibody responses induced by dietary antigen. Immunol. Lett. 132: 45-52, 2010.
  • Kobayashi S, Nagai T, Konishi Y, Tanabe S, Morimoto K and Ogihara T. Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes. J Pharm Pharmacol 64: 52-60, 2011.
  • Saito, K., Ohta, Y., Sami, M., Kanda, T. and Kato, H. Effect of mild restriction of food intake on gene expression profile in the liver of young rats: reference data for in vivo nutrigenomics study. Brit J Nutr 104(7):941-950, 2010.
  • Oka T, Fujimoto M, Nagasaka R, Ushio H, Hori M, Ozaki H. Cycloartenyl ferulate, a component contained in gamma-oryzanol, derived from rice bran oil, attenuates mast cell degranulation. Phytomedicine 17(2):152-156, 2010.
  • Dong, Y., Wu, T., Ni, Y.H., Kato, H., Fu, Z.W. Effect of fasting on the peripheral circadian gene expression in rats. Biol. Rhythm Res. 41:41-47, 2010.
  • Wu, T., Ni, Y., Dong, Y., Kato, H. and Fu, Z.W. Regulation of circadian gene expression in the kidney by light and food cues in rats. Am J Physiol Regul Integr Comp Physiol 298:635-641, 2010.
  • Abe, K., Kato, H., Yasuoka, A. and Nakai, Y. Genomics applied to nutrients and functional foods in Japan: State of the art. In: Genomics, proteomics, and metabolomics in nutraceuticals and functional foods. Bagchi, D., Lau, F.C. and Bagchi, M (eds) Wiley-Blackwell, U.S.A. pp127-154, 2010.
  • Hirao, T., Watanabe, S., Temmei, Y., Hiramoto, M. and Kato, H. Qualitative PCR methods for detecting major food allergens (peanut, soybean, and wheat) by using internal transcribed spacer region. J AOAC Int 92:1464-1472, 2009
  • Otani, L., Ninomiya, T., Murakami, M., Osajima, K., Kato, H. and Murakami, T. Sardine peptide with angiotensin I converting enzyme inhibitory activity improves glucose tolelance in stroke-prone spontaneously hypertensive rats. Biosci Biotechnol Biochem 73:2203-2209, 2009.
  • Hideo Ozawa, Shugo Watabe, and Yoshihiro Ochiai: Thermal stability of the synthetic peptides with the sequence of fish fast skeletal muscle tropomyosin. Fish Sci 75:1029-1037, 2009.
  • Xiao-Feng Guo, Hitoshi Aoki, Toshihiko Hagiwara, Kazuaki Masuda, and Shugo Watabe. Identification of high γ-aminobutyric acid producing marine yeast strains by physiological and biochemical characteristics and gene sequence analyses. Biosci Biotechnol Biochem 73:1527-1534, 2009.
  • Misako Nakaya, Yoji Igarashi, Shigeharu Kinoshita, Shoichiro Ishizaki, and Shugo Watabe: Identification of pufferfish species by single-strand conformation polymorphism of mitochondrial 16S rRNA gene. In “Proceedings of the 5th World Fisheries Congress”, 4c_0834_438, Yokohma, October 20-24, 2008, 2009.
  • Toshitaka Mochizuki, Hideyuki Arima, Katsuya Fukami, Yasuhiro Funatsu, and Shugo Watabe: The effects of organic acids on the quality of fish sauces made from the meat of different pufferfish species. In “Proceedings of the 5th World Fisheries Congress”, 4d_0887_354, Yokohma, October 20-24, 2008, 2009.
  • Ogihara T, Kano T, Wagatsuma T, Wada S, Yabuuchi H, Enomoto S, Morimoto K, Shirasaka Y, Kobayashi S, Tamai I. Oseltamivir (tamiflu) is a substrate of peptide transporter 1. Drug Metab Dispos 37(8):1676-1681, 2009.
  • Shiokawa A, Tanabe K, Tsuji NM, Sato R, Hachimura S. IL-10 and IL-27 producing dendritic cells capable of enhancing IL-10 production of T cells are induced in oral tolerance. Immunol Lett 30:125(1):7-14, 2009.
  • Tsuda M, Hosono A, Yanagibashi T, Hachimura S, Hirayama K, Umesaki Y, Itoh K, Takahashi K, Kaminogawa S. Intestinal Bifidobacterium association in germ-free T cell receptor transgenic mice down-regulates dietary antigen-specific immune responses of the small intestine but enhances those of the large intestine. Immunobiology 214(4):279-289, 2009.
  • Iwabuchi N, Takahashi N, Xiao JZ, Yonezawa S, Yaeshima T, Iwatsuki K, Hachimura S. Suppressive effects of Bifidobacterium longum on the production of Th2-attracting chemokines induced with T cell-antigen-presenting cell interactions. FEMS Immunol Med Microbiol 55(3):324-334, 2009.
  • Yanagibashi T, Hosono A, Oyama A, Tsuda M, Hachimura S, Takahashi Y, Itoh K, Hirayama K, Takahashi K, Kaminogawa S. Bacteroides induce higher IgA production than Lactobacillus by increasing activation-induced cytidine deaminase expression in B cells in murine Peyer’s patches. Biosci Biotechnol Biochem 73(2):372-377, 2009.
  • H. Kanzato, S. Fujiwara, W. Ise, S. Kaminogawa, R. Sato, S. Hachimura. Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells. Immunobiology 213:399-408, 2008.
  • Ito, K. Sugawara, T. Shiroishi, M. Tokuda, N. Kurokawa, A., Misaka, T. Makyio, H. Yurugi-Kobayashi, T. Shimamura, T. Nomura, N. Murata, T. Abe, K. Iwata, S. Kobayashi, T. Advanced method for high-throughput expression of mutated eukaryotic membrane proteins in Saccharomyces cerevisiae. Biochem Biophys Res Commun 371:841-845, 2008.
  • Nishinoaki, M., Asakura, T., Watanabe, T., Kunizaki, E., Matsumoto, M., Eto, W., Tamura, T., Minami, M., Obata, A., Abe, K., and Funaki, J. Applying an Aspergillus saitoi protease preparation to soybean curd for modification of its functional and rheological properties. Biosci Biotechnol Biochem 72:587-590, 2008.
  • Koyama, S., Hata, S., Witt, C., Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., and Sorimachi, H. Muscle RING-Finger Protein MuRF1 as a Connector of Muscle Energy Metabolism and Protein Synthesis. J Mol Biol 376:224-1236, 2008.
  • Tamura, T., Asakura,T., Uemura, T., Ueda, T., Terauchi, T., Misaka, T., and Abe, K. Signal peptide peptidase and its homologues in Arabidopsis thaliana: plant tissue-specific expression and distinct subcellular localization. FEBS J 275:34-43, 2008.
  • Arai, S., Yasuoka, A., and Abe, K. Functional food science and food for specified health use policy in Japan: state of the art. Cur Opin Lipid 19:69-73, 2008.
  • Nakai, Y., Hashida, H., Kadota, K., Minami, M., Shimizu, K., Matsumoto, I., Kato, H., and Abe, K. Up-regulation of Genes Related to the Ubiquitin-Proteasome System in the Brown Adipose Tissue of 24-h-fasted Rats. Biosci Biotechnol Biochem 72:139-148, 2008.
  • Kato, H. Nutrigenomics: the cutting edge and Asian perspectives. Asia Pac J Clin Nutr 17(S1):12-15, 2008.
  • Hirao, T., Watanabe, S., Hiramoto, M., Taguchi, H., Temmei, Y. and Kato, H. Qualitative and quantitative PCR methods for detecting food allergens by using internal transcribed spacer region. J Clin Biochem Nutr 43(S1):227-231, 2008.
  • Mohammed Anwar Hossain, Daisuke Ikeda, Akira Nomura, Hideto Fukushima, and Shugo Watabe: cDNA cloning and complete primary structures of myosin heavy chains from brushtooth lizardfish (Saurida undosquamis) and wanieso lizardfish (S. wanieso) fast skeletal muscles Fish Sci 74:921-934, 2008.
  • Kazuaki Masuda, Guo Xiao Feng, Noboru Uryu, Toshihiko Hagiwara, and Shugo Watabe. Isolation of marine yeasts collected from the Pacific Ocean having a high production of γ-aminobutyric acid. Biosci Biotechnol Biochem 72:3265-3272, 2008.
  • Kobayashi S. and Konishi Y. Transepithelial transport of flavanone in intestinal Caco-2 cell monolayers. Biochem Biophys Res Commun 28:368(1):23-29, 2008.
  • Kobayashi S., Tanabe S., Sugiyama M., and Konishi Y. Transepithelial transport of hesperetin and hesperidin in intestinal Caco-2 cell monolayers. Biochim Biophys Acta 1778(1):33-41, 2008.

Papers written in Japanese

  • Aya Shiokawa and Satoshi Hachimura,
    Oral immunological tolerance induction and CD11b+ cell populations,
    Clinical Immunology and Allergology, Vol. 56, 351-358, 2011
  • Hisanori Kato,
    1.9 Transriptome analysis (Chapter 5: Functionality of soybeans, Section 1: Functionality of protein), “All about soybeans” (Edited by Keisuke Kitamura, et al.), Science Forum, pp.185-188, 2010
  • Shugo Watabe,
    Study on safety and security of seafood: Development of food safety science – for forecasting and controlling food-related risks (compiled by Research Center for Food Safety, The University of Tokyo), CMC Publishing, Tokyo, pp. 221-232, 2010
  • Hisanori Kato,
    Chapter 7 (Translation): Required amount of protein for adults Including the elderly, pregnant and lactating women, “WHO/FAO/UNU co-sponsored specialist conference report: Required amount of protein and amino acid” (The Translation Small Committee, The Japanese Society for Amino Acid Sciences), Ishiyaku Publishing, pp.79-102, 2009
  • Shugo Watabe,
    General composite, 1. Chemistry and biochemistry of aquatic life, Chapter 4: Chemistry and utilization of aquatic life, an Introduction to aquatic bioscience (complied by Katsumi Aida), Koseisha-Koseikaku, Tokyo, pp.132-134, 2009 (co-authoring)
  • Shugo Watabe,
    Preservation of seafood freshness, Chapter 4: Chemistry and utilization of aquatic life, an introduction to aquatic bioscience (compiled by Katsumi Aida), Koseisha-Koseikaku, Tokyo, pp.164-169, 2009 (co-authoring)
  • Shugo Watabe,
    Other Substances, 4. Safety of seafood, Chapter 4: Chemistry and utilization of aquatic life, an introduction to aquatic bioscience (compiled by Katsumi Aida), Koseisha-Koseikaku, Tokyo, pp.172-173, 2009 (co-authoring)
  • Hisanori Kato and Keiko Abe,
    Analysis of Nutrigenomics’ Array, “Genetic Medicine MOOK, Vol.10, DNA Chip/Microarray – Reality of Clinical Application” (compiled by Hiroyuki Aburatani), Medical Do, pp. 285-290, 2008
  • Yuji Omura, Mayu Watanabe, Takashi Kimiya, Yumiko Yamashita, Emiko Okazaki, Masakatsu Yamazawa, and Shugo Watabe,
    Water soluble component of Japanese common squid to promote browning of dried squid products, Fisheries Science, Vol. 74, 66-74, 2008